PATHOLOGY

Detailed explanation-1: -Blood that is about to be filtered enters a glomerulus, which is a tuft of blood capillaries (the smallest of blood vessels). The glomerulus is nestled inside a cup-like sac located at the end of each nephron, called a glomerular capsule.

Detailed explanation-2: -The glomerulus is a loop of capillaries twisted into a ball shape, surrounded by the Bowman’s capsule. This is where ultrafiltration of blood occurs, the first step in urine production. The filtration barrier consists of 3 components: Endothelial cells of glomerular capillaries.

Detailed explanation-3: -Bowman’s capsule encloses a cluster of microscopic blood vessels-capillaries-called the glomerulus, where wastes are filtered from the blood.