PATHOLOGY

Detailed explanation-1: -The proximal tubule also completes the reabsorption of glucose, amino acids, and important anions, including phosphate and citrate, because it is the sole site of transport of these filtered solutes. In addition to solute reabsorption and secretion, the proximal tubule is also a metabolic organ.

Detailed explanation-2: -The majority of solute and water reabsorption occurs in the proximal convoluted tubule. Sodium ions, which are the most plentiful cation (positively charged ion) in the tubular fluid, participate in most solute reabsorption.

Detailed explanation-3: -Proximal convoluted tubule is involved in active reabsorption of sodium. The majority (about 70%) of sodium is reabsorbed here, into the cytosol of the epithelial cells of the nephron.

Detailed explanation-4: -Most of the solute reabsorbed in the proximal tubule is in the form of sodium bicarbonate and sodium chloride, and about 70% of the sodium reabsorption occurs here.