PATHOLOGY

Detailed explanation-1: -The basic filtration unit of the kidney is called nephron. It is used to separate water, ions and small molecules from the blood, filter out wastes and toxins, and return the required molecules into the blood. Bowman’s capsule is a cup-like sack at the beginning of the tubular component of a nephron in the kidney.

Detailed explanation-2: -The glomerulus is clinically significant because it is the location where filtration in the kidney begins. All actions of the nephron downstream of the glomeruli rely on the passage of filtrate from the glomerular capillaries into Bowman’s space. Several diseases can affect the glomerulus.