USA HISTORY

Detailed explanation-1: -When Europeans began to explore and colonize other parts of the world, smallpox traveled with them. The native people of the Americas, including the Aztecs, were especially vulnerable to smallpox because they’d never been exposed to the virus and thus possessed no natural immunity.

Detailed explanation-2: -The Aztec had no immunity to European diseases. Smallpox spread among the indigenous people and crippled their ability to resist the Spanish. The disease devastated the Aztec people, greatly reducing their population and killing an estimated half of Tenochtitlán’s inhabitants.

Detailed explanation-3: -Spanish conquistadores commanded by Hernán Cortés allied with local tribes to conquer the Aztec capital city of Tenochtitlán. Cortés’s army besieged Tenochtitlán for 93 days, and a combination of superior weaponry and a devastating smallpox outbreak enabled the Spanish to conquer the city.

Detailed explanation-4: -The alliance between the Spaniards and Tlaxcalans is one of the most important events in Mexican history. This alliance of the Europeans with the Totonac and Tlaxcalan Indians gave birth to a formidable coalition which would eventually lead to the downfall and destruction of the entire Aztec Empire.

Detailed explanation-5: -Earlier, the successful conquest of Mexican Aztec and Peruvian Inca empires by a handful of Spanish conquistadors led by Hernando Cortes and Francisco Pizarro, respectively, resulted in large part from epidemics of smallpox and measles virus infection that decimated the native defenders.