USA HISTORY

Detailed explanation-1: -One of history’s deadliest diseases, smallpox is estimated to have killed more than 300 million people since 1900 alone. But a massive global vaccination campaign put an end to the disease in 1977-making it the first disease ever eradicated.

Detailed explanation-2: -Likewise, smallpox claimed the life of an Inca emperor and wiped out much of the Inca population in western South America. In Europe, smallpox is estimated to have claimed 60 million lives in the 18th century alone. In the 20th century, it killed some 300 million people globally.

Detailed explanation-3: -Between 20 and 60% of all those infected-and over 80% of infected children-died from the disease. During the 20th century, it is estimated that smallpox was responsible for 300–500 million deaths.

Detailed explanation-4: -Smallpox was a terrible disease. On average, 3 out of every 10 people who got it died. People who survived usually had scars, which were sometimes severe.