USA HISTORY

Detailed explanation-1: -In the years before English settlers established the Plymouth colony (1616–1619), most Native Americans living on the southeastern coast of present-day Massachusetts died from a mysterious disease. Classic explanations have included yellow fever, smallpox, and plague.

Detailed explanation-2: -Diseases such as treponemiasis and tuberculosis were already present in the New World, along with diseases such as tularemia, giardia, rabies, amebic dysentery, hepatitis, herpes, pertussis, and poliomyelitis, although the prevalence of almost all of these was probably low in any given group.

Detailed explanation-3: -Native Americans suffered 80-90% population losses in most of America with influenza, typhoid, measles and smallpox taking the greatest toll in devastating epidemics that were compounded by the significant loss of leadership.

Detailed explanation-4: -Native Americans often contracted infectious disease through trading and exploration contacts with Europeans, and these were transmitted far from the sources and colonial settlements, through exclusively Native American trading transactions.