USA HISTORY

Detailed explanation-1: -Although the colonists suffered diseases of their own early on, they were largely immune to the microbes they brought over to the New World. The local Native American populations, however, had no such immunity to diseases like smallpox, tuberculosis, measles, cholera, and the bubonic plague.

Detailed explanation-2: -Native Americans suffered 80-90% population losses in most of America with influenza, typhoid, measles and smallpox taking the greatest toll in devastating epidemics that were compounded by the significant loss of leadership.

Detailed explanation-3: -The Native Americans were forced to give up their lands so the colonists could grow even more tobacco. In addition to their desire for land, the English also used religion to justify bloodshed. In 1637, New England Puritans exterminated thousands of Pequot Indians, including women and children.

Detailed explanation-4: -When the Europeans arrived, carrying germs which thrived in dense, semi-urban populations, the indigenous people of the Americas were effectively doomed. They had never experienced smallpox, measles or flu before, and the viruses tore through the continent, killing an estimated 90% of Native Americans.