MEDICINE
CARDIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Child less than 1 yo have decreased risk of coronary aneurysm
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Majority of small coronary aneurysms regress back to normal coronary vessels
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Immunoglobulins must be given within first 20 days of fever
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Approx. 20% of untreated kids will develop coronary aneurysms
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If aneurysms are small, aspirin therapy can be stopped at 8 weeks
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Detailed explanation-1: -Cardiovascular consequences of Kawasaki disease All cardiac tissues are involved in the acute inflammatory phase of the disease. 9 Vasculitis causes destruction of the normal arterial architecture and is followed by aneurysmal dilatation, particularly affecting the proximal coronary arteries.
Detailed explanation-2: -Kawasaki disease (KD) is now a common cause of acquired heart disease in children. Coronary artery involvement is the most serious complication in children with KD. Several non-coronary complications have now been identified in this condition but these are often overlooked.
Detailed explanation-3: -Kawasaki disease (KD) is an acute vasculitis that preferentially affects medium‐sized arteries, particularly the coronary arteries (CA). CA involvement can range from transient mild dilatation or ectasia, occurring in up to 40% of patients, to giant coronary artery aneurysms (CAA).
Detailed explanation-4: -[1] About 15-25% of untreated children will go on to develop CAAs. [1] Specific factors lead to an increased risk of coronary artery aneurysms including [1][4][5][10][11][12]: Fever >8 days (most important risk factor)