GENERAL KNOWLEDGE

Detailed explanation-1: -Lock-and-key model is a model for enzyme-substrate interaction suggesting that the enzyme and the substrate possess specific complementary geometric shapes that fit exactly into one another. Enzymes are highly specific. They must bind to a specific substrate before they can catalyze a chemical reaction.

Detailed explanation-2: -Explanation: The lock and key model states that the active site of an enzyme precisely fits a specific substrate. The induced fit model states that the active site of an enzyme will undergo a conformational change when binding a substrate, to improve the fit.

Detailed explanation-3: -A Lock and Key analogy may be used to describe the fundamental action of a single substrate enzyme. In this case, the enzyme is the lock, and the substrate is the key. Only the correct size key, which is the substrate, enters the keyhole, which is the active site of the lock, which is the enzyme.

Detailed explanation-4: -In the lock and key model, the shape of the active site matches the shape of its substrate molecules. This makes enzymes highly specific – each type of enzyme can catalyse only one type of reaction (or just a few types of reactions).