GK
ECOLOGY BIODIVERSITY CONSERVATION ENVIRONMENTAL ISSUES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Phosphate
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ADP
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H2S
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CO2
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Detailed explanation-1: -H2S serves as an electron donor for the mitochondrial respiratory chain via sulfide quinone oxidoreductase and cytochrome c oxidase at low H2S levels. The latter enzyme is inhibited by high H2S concentrations, resulting in the reversible inhibition of electron transport and ATP production in mitochondria.
Detailed explanation-2: -Until recently, hydrogen sulfide (H2S) was exclusively viewed a toxic gas and an environmental hazard, with its toxicity primarily attributed to the inhibition of mitochondrial Complex IV, resulting in a shutdown of mitochondrial electron transport and cellular ATP generation.
Detailed explanation-3: -Cyanide: inhibits terminal electron transfer to oxygen, Complex IV.
Detailed explanation-4: -In SMCs, mitochondrial CSE translocation and H2S production confer resistance to hypoxia by increasing ATP synthesis. By sensing the oxygen levels in mitochondria, H2S regulates ATP production under different conditions, thereby fulfilling the roles of an oxygen sensor (41) and a regulator of energy metabolism.