GK
VITAMINS MINERALS COENZYMES AND DEFICIENCY DISEASES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Lipoic acid is a co-factor of the
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pyruvic dehydrogenase
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both (a) and (b)
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di-hydroorotate dehydrogenase
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Explanation:
Detailed explanation-1: -Lipoic acid is another B-complex vitamin, whose only known function is to participate in the oxidative decarboxylations of -ketoacids, principally conversion of pyruvate to acetyl-CoA, and -ketoglutarate to succi-nyl-CoA, two similar dehydrogenase complexes of the TCA cycle.
Detailed explanation-2: -Lipoic acid is a cofactor for five enzymes or classes of enzymes: pyruvate dehydrogenase, a-ketoglutarate dehydrogenase, the glycine cleavage system, branched chain keto acid dehydrogenase, and the alpha-oxo(keto)adipate dehydrogenase. The first two are critical to the citric acid cycle.
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