GK
VITAMINS MINERALS COENZYMES AND DEFICIENCY DISEASES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What transports copper from the intestinal cells to the liver?
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Albumin
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Acrolein
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Secretin
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Ceruloplasmin
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Explanation:
Detailed explanation-1: -Copper is transported by albumin and transcuprein (recently shown to be a macroglobulin) (21). Hepatic copper is likely taken up by CTR1 and by ATOX1 delivered to the TGN and ATP7B for ceruloplasmin synthesis or to the canalicular membrane by COMMD1 en route to bile.
Detailed explanation-2: -Ceruloplasmin (Cp) is a copper-transport protein with ferric oxidase activity found in high concentrations in the plasma of all vertebrates.
Detailed explanation-3: -Ceruloplasmin (CP) CP is a serum 2-glycoprotein that carries more than 95% of the copper present in plasma and is believed to have an active role in the regulation of copper and iron homeostasis.
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