GENERAL KNOWLEDGE

GK

VITAMINS MINERALS COENZYMES AND DEFICIENCY DISEASES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which bone cell secrete collagen and then pull calcium and phosphorus from the blood to form a hardened material that provide structure of bone?
A
Osteocalst
B
Osteoblast
C
both (a) and (b)
D
none of these
Explanation: 

Detailed explanation-1: -Osteoblasts (Ob) secrete collagenous (Col1) and noncollagenous proteins such as osteocalcin (OCN), osteopontin (OSP), osteonectin (OSN), bone sialoprotein (BSP), and bone morphogenetic proteins (BMP). Osteocytes (Ot) are located within lacunae surrounded by mineralized bone matrix (B).

Detailed explanation-2: -Osteoblasts are bone cells that are responsible for bone formation. Osteoblasts synthesize and secrete the organic part and inorganic part of the extracellular matrix of bone tissue, and collagen fibers.

Detailed explanation-3: -Osteoblasts are cells responsible for the secretion and deposition of bone morphogenetic proteins (BMPs) into the extracellular matrix during bone formation.

Detailed explanation-4: -Osteoblasts are the bone cells derived from osteochondral progenitor cells that form the bone through a process called ossification.

Detailed explanation-5: -Osteoblasts are the cells that synthesize bone matrix proteins and are active in bone matrix mineralization. Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals).

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