MICROANATOMY

Detailed explanation-1: -These naturally occurring antibodies are mainly IgM immunoglobulins. They attack and rapidly destroy red cells carrying the corresponding antigen. For example, anti-A attacks red cells of Group A or AB. Anti-B attacks red cells of Group B or AB.

Detailed explanation-2: -Blood group O is common, and individuals with this blood type will have both anti-A and anti-B in their serum. Blood group AB is the least common, and these individuals will have neither anti-A nor anti-B in their serum. ABO antibodies in the serum are formed naturally.

Detailed explanation-3: -The Anti-A, Anti-B, and Anti-A, B reagents are used in the red blood cell determination of the ABO blood group. They are used to determine the absence or presence of erythrocytic antigens A and/or B on the surface of human red blood cells.

Detailed explanation-4: -Anti-type B antibodies will recognize and bind to type B antigen. This will cause the red blood cells to agglutinate, or to clump up into a mass. Antibodies have the shape of the letter Y. Each of the short arms of the Y has a site that can bind to the antigen.