MICROANATOMY

Detailed explanation-1: -Osteoblasts are bone-forming cell, osteoclasts resorb or break down bone, and osteocytes are mature bone cells.

Detailed explanation-2: -Matured osteocytes are the most common cells in bone tissues, and the majority of receptor activities involved with bone function are available in these cells. Osteocytic necrosis also leads to trabecular bone decay, decreased bone formation, and malfunctioning loading.

Detailed explanation-3: -Osteocytes derive from osteoblasts, or bone-forming cells, and are essentially osteoblasts surrounded by the products they secreted. Cytoplasmic processes of the osteocyte extend away from the cell toward other osteocytes in small channels called canaliculi.

Detailed explanation-4: -Osteocytes are cells lying within the bone itself and are ‘entrapped’ osteoblasts. They are post-proliferative, representing the most mature differentiation state of osteoblast lineage. There are about 25, 000 osteocytes per mm3 of bone.

Detailed explanation-5: -The first type of bone formed developmentally is primary or woven bone (immature). This immature bone is later replaced by secondary or lamellar bone (mature).