MICROANATOMY

Detailed explanation-1: -Serotonin is transported by platelets and released upon activation. This induces constriction of injured blood vessels and enhances platelet aggregation to minimize blood loss.

Detailed explanation-2: -Elevated platelet serotonin levels promote clotting, which may be a potential underlying mechanism linking depression with CAD.

Detailed explanation-3: -Heparin is a natural anticoagulant of the body produced in the liver. It is normally found circulating through the bloodstream. It prevents the blood clotting in veins and arteries during normal circulation.

Detailed explanation-4: -Primary hemostasis (platelet clotting) That clot works much like a cork or bottle stopper, keeping blood in and debris or germs out. Primary hemostasis may also involve constriction (narrowing) of the damaged blood vessel, which can happen because of substances that activated platelets release.

Detailed explanation-5: -Prostacyclin produces vasodilation, and thromboxane A2 causes vasoconstriction. Prostacyclin inhibits platelet aggregation and produces vasodilation whereas thromboxane A2 and endoperoxides promote platelet aggregation and cause vasoconstriction.