MICROANATOMY

BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS

BLOOD

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
first red blood cells are formed in ____
A
liver
B
bone
C
lymph
D
None of the above
Explanation: 

Detailed explanation-1: -Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood.

Detailed explanation-2: -Data synthesis: The yolk sac is the first site of blood-cell production during murine and human ontogeny. Primitive erythroid cells originate in the yolk sac and complete their maturation, including enucleation, in the bloodstream.

Detailed explanation-3: -The fetal liver is the site of development of adult-type red blood cells, which mature within “erythroblastic islands” (EBIs). EBIs, which are also found in bone marrow and spleen, are 3-dimensional structures containing a central macrophage surrounded by erythroid cells at various stages of maturation.

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