BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS
BLOOD
Question
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Given the following events:Fibrinogen forms bridges between fibrinogen receptors platelets stick to collagen platelets release ADP and thromboxane Choose the arrangement that lists the events in the order they occur during platelet plug formation
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2, 1, 3
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2, 3, 1
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3, 2, 1
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3, 1, 2
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Explanation:
Detailed explanation-1: -1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade. 4) Formation of “fibrin plug” or the final clot.
Detailed explanation-2: -Platelet plug formation: Fibrinogen forms bridges between activated platelets to form the platelet plug.
Detailed explanation-3: -It builds glycoprotein IIb/IIIa in the platelet membrane and constitutes a fibrinogen receptor, which also exhibits an ability to bind the von Willebrand factor, fibronectin, and thrombospondin. Activated GPIIb-IIIa binds fibrinogen or von Willebrand factor, which forms molecular bridges between aggregating platelets.
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