MICROANATOMY

Detailed explanation-1: -When this antigen exists for one group, an antibody for the other group will exist as well. Thus, when the blood of the opposing group enters the body, the antibody attacks the antigen and they form a clump. This is called as agglutination.

Detailed explanation-2: -During an ABO incompatibility reaction, the red blood cells inside your circulatory system break down. Blood clotting may occur throughout your body, shutting off the blood supply to vital organs or causing a stroke. Too much blood clotting can use up clotting factors and leave you at risk of excessive bleeding.

Detailed explanation-3: -Mixing incompatible blood groups leads to blood clumping or agglutination, which is dangerous for individuals. Nobel Laureate Karl Landsteiner was involved in the discovery of both the AB0 blood group (in 1901) and Rh blood group (in 1937).

Detailed explanation-4: -The agglutination indicates that the blood has reacted with a certain antibody and is therefore not compatible with blood containing that kind of antibody. If the blood does not agglutinate, it indicates that the blood does not have the antigens binding the special antibody in the reagent.