MICROANATOMY

Detailed explanation-1: -Platelets are formed when cytoplasmic fragments of megakaryocytes, which are very large cells in the bone marrow, pinch off into the circulation as they age. They are stored in the spleen. Some evidence suggests platelets may also be produced or stored in the lungs, where megakaryocytes are frequently found.

Detailed explanation-2: -Platelets are the smallest blood cells; they are cytoplasmic fragments derived from their bone marrow precursor, the megakaryocyte. Resting platelets have a smooth disk shape and are 3.6 ± 0.7 µm in diameter.

Detailed explanation-3: -Platelets are not actually cells, but cytoplasmic fragments of large cells known as megakaryocytopoiesis. The platelets themselves are incapable of mitotic division since they lack a nucleus and have no DNA.

Detailed explanation-4: -Platelet Structure and Distribution Platelets are irregularly shaped, have no nucleus, and typically measure only 2–3 micrometers in diameter. Platelets are not true cells, but are instead classified as cell fragments produced by megakaryocytes. Because they lack a nucleus, they do not contain nuclear DNA.

Detailed explanation-5: -Platelets are produced from very large bone marrow cells called megakaryocytes. As megakaryocytes develop into giant cells, they undergo a process of fragmentation that results in the release of over 1, 000 platelets per megakaryocyte.