MICROANATOMY

Detailed explanation-1: -Erythropoietin (EPO) is a glycoprotein hormone, naturally produced by the peritubular cells of the kidney, that stimulates red blood cell production. Renal cortex peritubular cells produce most EPO in the human body. PO2 directly regulates EPO production. The lower the pO2, the greater the production of EPO.

Detailed explanation-2: -Healthy kidneys produce a hormone called erythropoietin or EPO, which stimulates the bone marrow to make red blood cells needed to carry oxygen (O2) throughout the body.

Detailed explanation-3: -Erythropoietin (EPO) is a hormone that is produced predominantly by specialised cells called interstitial cells in the kidney. Once it is made, it acts on red blood cells to protect them against destruction. At the same time it stimulates stem cells of the bone marrow to increase the production of red blood cells.

Detailed explanation-4: -Erythropoietin is distinct among the hematopoietic growth factors because it is produced primarily in the kidneys rather than the bone marrow.

Detailed explanation-5: -The erythropoietin test measures the amount of a hormone called erythropoietin (EPO) in blood. The hormone tells stem cells in the bone marrow to make more red blood cells. EPO is made by cells in the kidney. These cells release more EPO when blood oxygen level is low.