MICROANATOMY

Detailed explanation-1: -Clumping (agglutination) of red blood cells is frequently caused by cold agglutinins. Cold agglutinins are IgM antibodies that may arise following viral or Mycoplasma infections, or in the setting of plasma cell or lymphoid neoplasms. Agglutination of red cells can interfere with red blood cell indices.

Detailed explanation-2: -The agglutination of red blood cells (RBCs) is specifically called hemagglutination. What causes the agglutination of RBCs can be attributed to hemagglutinins (a group of agglutinins). Hemagglutinins are glycoproteins that cause the red blood cells to stick together.

Detailed explanation-3: -When the antibodies bind to these antigens, they clump red blood cells together. This clumping of cells is referred to as agglutination. By using this pattern of agglutination, we can determine the blood type of a person by mixing a small sample of their blood with anti-A and anti-B antibodies.

Detailed explanation-4: -Agglutination is defined as specific clumping of particulates such as cells or cell-sized objects. Antibodies and lectins are two types of reagents which, because they bind to specific targets, can cause agglutination of particulates.

Detailed explanation-5: -Agglutination refers to the phenomenon where red blood cells stick together in three-dimensional clumps. Agglutination is due to the binding of antibodies to red blood cells.