MICROANATOMY

Detailed explanation-1: -Spleen is known as the RBC graveyard. RBCs are destroyed in the spleen.

Detailed explanation-2: -Erythrocytes or red blood cell’s life span is 120 days. After 120 days in the circulation, they are removed by macrophages which are a type of myeloid phagocytic cells. They are located primarily in the liver, spleen, and bone marrow. The worn-out RBC is destroyed in the spleen and liver.

Detailed explanation-3: -Healthy blood cells simply pass through the spleen and continue to circulate throughout your bloodstream. Blood cells that can’t pass the test will be broken down in your spleen by macrophages. Macrophages are large white blood cells that specialize in destroying these unhealthy red blood cells.

Detailed explanation-4: -Enlarged spleen or liver: Your liver and spleen filter red blood cells as the cells move through your body. Red blood cells that are damaged or dying are trapped by your spleen and liver, which destroy the cells.