MICROANATOMY

Detailed explanation-1: -1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade. 4) Formation of “fibrin plug” or the final clot.

Detailed explanation-2: -Hemostasis is the natural process that stops blood loss when an injury occurs.It involves three steps: (1) vascular spasm ( vasoconstriction ); (2) platelet plug formation; and (3) coagulation. Vasoconstriction is a reflex in which blood vessels narrow to increase blood pressure.

Detailed explanation-3: -The platelet plug is the first step to stop bleeding, but it isn’t stable enough to stay in place without help. The next step, which stabilizes the plug, is secondary hemostasis. This step, sometimes called coagulation, involves molecules in your blood called “coagulation factors.”

Detailed explanation-4: -Generalized vasoconstriction usually results in an increase in systemic blood pressure, but it may also occur in specific tissues, causing a localized reduction in blood flow. The extent of vasoconstriction may be slight or severe depending on the substance or circumstance.