MICROANATOMY

Detailed explanation-1: -The mechanism of hemostasis can divide into four stages. 1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade. 4) Formation of “fibrin plug” or the final clot.

Detailed explanation-2: -The three steps to platelet plug formation are platelet adherence, activation, and aggregation.

Detailed explanation-3: -Platelet plug formation, also known as primary hemostasis, is the first step of hemostasis and is the process where a platelet plug forms to prevent further loss of blood from a damaged vessel. It is divided into five stages: endothelial injury, exposure, adhesion, activation, and aggregation.

Detailed explanation-4: -Blood clotting involves three steps. First, vascular spasm slows the flow of blood. Next, a platelet plug forms to temporarily seal small openings in the vessel. Coagulation then enables the repair of the vessel wall once the leakage of blood has stopped.