MICROANATOMY

Detailed explanation-1: -Unfractionated heparin is an anticoagulant indicated for both the prevention and treatment of thrombotic events such as deep vein thrombosis (DVT) and pulmonary embolism (PE) as well as atrial fibrillation (AF).

Detailed explanation-2: -Heparin is a sulfated polysaccharide with a molecular weight range of 3000 to 30 000 Da (mean, 15 000 Da). It produces its major anticoagulant effect by inactivating thrombin and activated factor X (factor Xa) through an antithrombin (AT)-dependent mechanism.

Detailed explanation-3: -Heparin, an anticoagulant used in surgery, kidney dialysis and other clinical applications, is produced from a single source of raw material: porcine intestine – a by-product of the pork industry.

Detailed explanation-4: -Heparin is a naturally occurring anticoagulant, produced by basophils and mast cells, which are composed of a highly sulfated glycosaminoglycan biologic substance.