MICROANATOMY

Detailed explanation-1: -Platelets are produced from very large bone marrow cells called megakaryocytes.

Detailed explanation-2: -The megakaryocyte is the hematopoietic cell that produces platelets.

Detailed explanation-3: -Platelets are formed and released into the bloodstream by precursor cells called megakaryocytes that reside within the bone marrow. The production of platelets by megakaryocytes requires an intricate series of remodeling events that result in the release of thousands of platelets from a single megakaryocyte.

Detailed explanation-4: -Platelets come from larger progenitor cells called megakaryocytes, and platelet production represents the final stage of megakaryocyte development (Fig. 1).

Detailed explanation-5: -Thrombopoiesis is the generation of platelets from megakaryocytes. Megakaryocytes comprise approximately 0.05%–0.1% of hematopoietic cells in a normal bone marrow and are highly specialized large nuclear cells (50–100 m in diameter) that differentiate to produce platelets.