MICROANATOMY

Detailed explanation-1: -The muscles of the heart, termed the myocardium, make up the middle and thickest layer of the heart wall. This layer lies between the single-cell endocardium layer, which lines the inner chambers, and the outer epicardium, which makes up part of the pericardium that surrounds and protects the heart.

Detailed explanation-2: -The myocardium is thickest in the left ventricle, as the left ventricle must create a lot of pressure to pump blood into the aorta and throughout systemic circulation. Cardiac muscle has a high density of mitochondria and a large blood supply, which keep it functioning continuously.

Detailed explanation-3: -The endocardium connects to blood vessels that supply the heart muscle and contributes to the regulation of heart contractions. The myocardium is the thickest layer of the heart wall, which is made up of myocytes, or cardiac muscle cells.

Detailed explanation-4: -At the centimeter scale, tissue engineering aims for compact constructs of a thickness comparable to that of the human myocardium ( 1.5 cm).

Detailed explanation-5: -Endocardium is thicker in the atria than in the ventricles, in the left-than in the corresponding right-sided chambers, and in the outflow tracts than in the inflow tracts of the ventricles.