MICROANATOMY

Detailed explanation-1: -Desmosomes Connect Intermediate Filaments from Cell to Cell The particular type of intermediate filaments attached to the desmosomes depends on the cell type: they are keratin filaments in most epithelial cells, for example, and desmin filaments in heart muscle cells.

Detailed explanation-2: -Desmosomes are one of four intercellular junctions present on the lateral side of neighboring polarized epithelial cells. Tight junctions and adherens junctions (AJs) are restricted to the apical domain, where they form the epithelial barrier and organize cortical actin, respectively.

Detailed explanation-3: -Intercalated disc contains gap junctions and desmosomes for depolarization and muscle contraction.

Detailed explanation-4: -Intercalated Disks: Structure and Components Desmosomes are major cell adhesion junctions that anchor cell membranes to the intermediate filament network, particularly in tissues undergoing constant physical stress, such as skin and heart (Jamora and Fuchs 2002).