MICROANATOMY

Detailed explanation-1: -Neutrophils. Neutrophils are the most abundant white blood cell in humans and arise from granulocytes. They are also phagocytic in nature, and Metchnikoff called neutrophils the “archetypal phagocyte”.

Detailed explanation-2: -Neutrophils, also known as polymorphonuclear leukocytes (PMNs), have long been considered as the short-lived, nonspecific white cells that form pus-and also happen to kill invading microbes. Indeed, neutrophils were often neglected (and largely not considered) as immune cells.

Detailed explanation-3: -Macrophages work as innate immune cells through phagocytosis and sterilization of foreign substances such as bacteria, and play a central role in defending the host from infection.

Detailed explanation-4: -Neutrophils are important effector cells in the innate arm of the immune system (Mayadas et al., 2014). They constantly patrol the organism for signs of microbial infections, and when found, these cells quickly respond to trap and kill the invading pathogens.

Detailed explanation-5: -Neutrophils are highly motile phagocytic cells that constitute the first line of defense of the innate immune system.