MICROANATOMY

Detailed explanation-1: -Erythropoietin (Epo) is a glycoprotein hormone produced in the kidney that acts on erythroid progenitor cells in the bone marrow. A negative feedback system, in which tissue oxygenation controls Epo production and Epo controls red blood cell (RBC) production, provides homeostasis in oxygen delivery to body tissues.

Detailed explanation-2: -Angiotensin II (Ang II) is thought to stimulate erythropoiesis by two means. First, Ang II increases Epo production.

Detailed explanation-3: -Erythropoietin is a hormone that your kidneys naturally make to stimulate the production of red blood cells. High or low levels of erythropoietin can cause health problems. A healthcare provider can measure your erythropoietin levels with a blood test.