MICROANATOMY

Detailed explanation-1: -Parenchyma (centers of hematopoietic cells) and stroma are differentiated in the bone marrow structure like in any other organ. Stromal component is represented by bone, fat and connective tissues, blood vessels, reticular fibers, and other types of cells (Fig. 1).

Detailed explanation-2: -Clusters of haematopoietic cells known as haematopoietic islands are widely distributed throughout the loose connective tissue network observed in red marrow. These islands are found next to relatively large, yet thin walled, sinusoids that also communicate with nutrient vessels of the bone.

Detailed explanation-3: -The target tissue within the hematopoietic system are myeloid and erythroid stem cells.