MICROANATOMY

Detailed explanation-1: -If bilirubin is found in your urine, it may be a sign that you have: A liver disease, such as hepatitis or cirrhosis. A blockage in your bile ducts, the small tubes that carry bile out of your liver.

Detailed explanation-2: -The body produces bilirubin when it breaks down red blood cells, and the liver helps excrete it. High bilirubin levels can result from liver disease, pancreatitis, some cancers, and other health problems. High bilirubin can lead to jaundice. This disorder is easily recognizable due to a yellowing of the skin and eyes.

Detailed explanation-3: -Formation of Bilirubin Roughly, 80% of bilirubin is made from the breakdown of hemoglobin in senescent red blood cells, and prematurely destroyed erythroid cells in the bone marrow. The remainder originates from the turnover of various heme-containing proteins found in other tissues, primarily the liver and muscles.

Detailed explanation-4: -Bilirubin (bil-ih-ROO-bin) is a yellowish pigment that is made during the breakdown of red blood cells. Bilirubin passes through the liver and is eventually excreted out of the body. Higher than usual levels of bilirubin may indicate different types of liver or bile duct problems.