MICROANATOMY

Detailed explanation-1: -bone marrow becomes the major factor in hematopoiesis, and by birth there is little or no hematopoiesis in the liver and spleen.-mesonephros (AGM) region (mesoblastic phase), then to the fetal liver (hepatic phase), and finally resides in the bone marrow (medullary phase).

Detailed explanation-2: -The most common site of blood cell production is the spongy tissue inside of your bones called bone marrow. Hematopoiesis that occurs in your bone marrow is called medullary hematopoiesis. Blood cells get made in your bone marrow and released into your bloodstream.

Detailed explanation-3: -MARROW REGENERATION myeloid period of hematopoiesis starts about the fifth fetal month. The cartilage of the bone primordia is resorbed, producing blood-forming centers composed of the mesenchymal cells and the myeloid cells.

Detailed explanation-4: -The liver and spleen are the main sites of extramedullary hematopoiesis. Other organs such as the lungs, kidney, and the peritoneal cavity can also become the sites of hematopoiesis when in diseased states.