MICROANATOMY

Detailed explanation-1: -Plasma cells are differentiated B-lymphocyte white blood cells capable of secreting immunoglobulin or antibodies. These cells play a significant role in the adaptive immune response, namely, being the main cells responsible for humoral immunity.

Detailed explanation-2: -Plasma cells develop from B cells that have been activated. A plasma cell is a type of white blood cell.

Detailed explanation-3: -Plasma cells (PCs) represent the terminal differentiation step of mature B lymphocytes. These cells are most recognizable for their extended lifespan as well as their ability to secrete large amounts of antibodies (Abs) thus positioning this cell type as a key component of humoral immunity.

Detailed explanation-4: -As the primary response proceeds, the antibody produced in a B cell can change to IgG, IgA, or IgE by the process known as class switching. Class switching is the change of one antibody class to another.

Detailed explanation-5: -Antibodies are naturally produced by plasma cells within the human body to mediate an adaptive immune response against invading pathogens. There are five predominant antibodies produced, each specialized to execute certain functions.