MICROANATOMY

BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS

LYMPH NODES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How does the HIV virus attack?
A
it kills the antibodies in your body
B
it prevents you from making new antibodies
C
it prevents your body from remembering the diseases you have already had
D
it attacks WBCs so your body can’t fight infection
Explanation: 

Detailed explanation-1: -White blood cells are an important part of the immune system. HIV infects and destroys certain white blood cells called CD4+ cells. If too many CD4+ cells are destroyed, the body can no longer defend itself against infection. The last stage of HIV infection is AIDS (acquired immunodeficiency syndrome).

Detailed explanation-2: -To infect cells, the HIV protein envelope (Env) binds to the primary cellular receptor CD4 and then to a cellular coreceptor. This sequential binding triggers fusion of the viral and host cell membranes, initiating infection.

Detailed explanation-3: -HIV causes your body to produce more CD4 cells to fight this new infection. These new cells provide more cells for HIV to infect and reproduce. The body responds by making even more cells to fight the new virus etc. This cycle continues every day and slowly, usually over many years, the immune system becomes worn out.

Detailed explanation-4: -Why is the immune system unable to combat HIV? Of the cells, HIV chooses human immune system cells as its host. Once integrated into the host genome of these immune cells, the virus´s genes become insusceptible to attack.

There is 1 question to complete.