MICROANATOMY

Detailed explanation-1: -Talk to your doctor if you have lupus symptoms. Lupus is a chronic disease with no cure. This means that you can manage it with treatment, but it will not go away. Treatment can help improve your symptoms, prevent flares, and prevent other health problems often caused by lupus.

Detailed explanation-2: -The first medication used for lupus, quinine (an antimalarial), was described by Payne in 1894 (Payne, 1894). Four years later, the use of salicylates in conjunction with quinine was a significant step in lupus therapy (Radcliffe-Crocker, 1898).

Detailed explanation-3: -In 1951, the antimalarial drug, quinacrine, was used for the treatment of DLE. This lead to further realization that chloroquine and hydroxychloroquine (plaquenil) were highly useful to treat various forms of the disease. 1952 began the first use of immunosuppression to treat lupus, with the use of nitrogenous mustard.

Detailed explanation-4: -As of 1963, there were few treatments for SLE. Everyone with a lupus diagnosis was placed on a high dose of oral prednisone. Hydroxychloroquine and cyclophosphamide were also offered, in addition to aspirin for arthritis pain.