MICROANATOMY

Detailed explanation-1: -IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Interferons are named for their ability to “interfere” with viral replication by protecting cells from virus infections.

Detailed explanation-2: -Interferons act via autocrine and paracrine pathways to induce an antiviral state in infected cells and in neighboring cells containing interferon receptors. Interferons are the frontline defenders against viral infection and their primary function is to locally restrict viral propagation.

Detailed explanation-3: -The various forms of interferon are the body’s most rapidly produced and important defense against viruses. Interferons can also combat bacterial and parasitic infections, inhibit cell division, and promote or impede the differentiation of cells.

Detailed explanation-4: -Interferons are proteins that are part of your natural defenses. They tell your immune system that germs or cancer cells are in your body. And they trigger killer immune cells to fight those invaders. Interferons got their name because they “interfere” with viruses and keep them from multiplying.

Detailed explanation-5: -Type I IFNs are important for host defence against viruses, through the induction of antiviral effector molecules that are encoded by IFN-stimulated genes. These IFNs can, however, cause immunopathology in acute viral infections.