MICROANATOMY

Detailed explanation-1: -Peyer’s patches are found in the wall of the small intestine. Function. The macrophages of Peyer’s patches are in an ideal position to capture and destroy bacteria (always present in tremendous numbers in the intestine), thereby preventing them from penetrating the intestinal wall. Mucosa-associated lymphatic tissue.

Detailed explanation-2: -Gut-associated lymphoid tissue (GALT) Peyer’s patches (PP) are visible lymphatic structures that were first discovered in the human small intestine (Cornes, 1965). Due to the capability of PP to manage antigens and bacteria in the luminal areas, they are considered as the immunosensors in the intestine.

Detailed explanation-3: -Peyer’s patches also referred to as aggregated lymphoid nodules form a significant portion of the immune system by supervising the intestinal bacteria population and checking the growth of the pathogenic bacteria in the intestines.

Detailed explanation-4: -In the Peyer’s patches, the B lymphocytes reside in the germinal centers of these follicles where their maturation takes place, and the T lymphocytes are in the parafollicular zone. The Peyer’s patches at their apices contain M (microfold) cells, enterocytes expressing MHC class II.