MICROANATOMY

Detailed explanation-1: -Always economical, your spleen saves any useful components from the old cells, such as iron. It stores iron in the form of ferritin or bilirubin, and eventually returns the iron to your bone marrow, where hemoglobin is made.

Detailed explanation-2: -The liver is a major storage organ of iron, in which excess iron is stored as ferritin and hemosiderin.

Detailed explanation-3: -Macrophages in the red pulp of the spleen destroy senescent red blood cells and recycle the stored iron to be further incorporated into maturating RBCs during erythropoiesis.

Detailed explanation-4: -It is one of the most common genetic disorders in the U.S. People with the disease accumulate too much iron in their blood and body. If left untreated, it can cause diseases to develop, such as osteoarthritis and osteoporosis, diabetes, liver disease, heart disease, enlarged spleen, and abnormal skin color.