MICROANATOMY

Detailed explanation-1: -The lymph nodes and other lymphatic structures like the spleen and thymus hold special white blood cells called lymphocytes. These can rapidly multiply and release antibodies in response to bacteria, viruses, and a range of other stimuli from dead or dying cells and abnormally behaving cells such as cancer cells.

Detailed explanation-2: -They also filter the lymph fluid and remove foreign material such as bacteria and cancer cells. When bacteria are recognized in the lymph fluid, the lymph nodes make more infection-fighting white blood cells. This causes the nodes to swell. The swollen nodes are sometimes felt in the neck, under the arms, and groin.

Detailed explanation-3: -Lymph nodes contain lymphocytes, a type of white blood cell, and are primarily made up of B cells and T cells. B cells are mainly found in the outer cortex where they are clustered together as follicular B cells in lymphoid follicles, and T cells and dendritic cells are mainly found in the paracortex.

Detailed explanation-4: -Lymph nodes are small, bean-shaped masses of lymphatic tissue along lymph vessels. They store lymphocytes and filter waste, bacteria and damaged cells (including cancer cells) from lymph.

Detailed explanation-5: -Lymphocytes arise from stem cells in bone marrow, and differentiate in the central lymphoid organs (yellow), B cells in bone marrow and T cells in the thymus.