MICROANATOMY

Detailed explanation-1: -Lymph nodes are small bean-shaped tissues found along the lymphatic vessels. The lymph nodes act as filters. Various immune system cells trap germs in the lymph nodes and activate the creation of special antibodies in the blood.

Detailed explanation-2: -Lymph node structure The outer layer (Cortex) contains the B-cell areas, or follicles. The middle layer (Paracortex) is mostly populated by T cells and dendritic cells (Figure 1). The paracortex also contains specialised blood vessels (high endothelial venules) through which many B and T cells enter the node.

Detailed explanation-3: -Antibodies produced in the course of a humoral immune response also leave the lymph node predominantly via the efferent lymphatic vessel to systemically fight the infection.