MICROANATOMY

Detailed explanation-1: -Stem cells mostly live in the bone marrow (the spongy center of certain bones). This is where they divide to make new blood cells. Once blood cells mature, they leave the bone marrow and enter the bloodstream.

Detailed explanation-2: -Lymphocytes arise from stem cells in bone marrow, and differentiate in the central lymphoid organs (yellow), B cells in bone marrow and T cells in the thymus.

Detailed explanation-3: -Inside the bone marrow, blood stem cells divide and mature to make new blood cells. During this process, the cells become either lymphocytes (a kind of white blood cell) or other blood-forming cells.

Detailed explanation-4: -T cells are derived from bone marrow stem cells, but mature in the thymus and can be divided into two main subsets based on surface markers, CD8 and CD4. CD8+ cells, also known as cytotoxic T lymphocytes (CTLs), are able to interact with target cells and initiate their demise.