MICROANATOMY

BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS

LYMPHATIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Due to a genetic mutation, B Cells are not able to produce plasma cells after connecting with an antigen-bearing T cell. How would this affect the body and the maintenance of homeostasis?
A
It would have no effect.
B
B cells would not be able to connect with an antigen to identify non-self or self
C
Antibodies would not be able to be used to tag antigens to help destroy them
D
None of the above
Explanation: 

Detailed explanation-1: -Vertebrates inevitably die of infection if they are unable to make antibodies. Antibodies defend us against infection by binding to viruses and microbial toxins, thereby inactivating them (see Figure 24-2).

Detailed explanation-2: -Follicular helper T Cells (Tfh). There, they induce the formation of germinal centers, the transformation of B Cells into plasma cells, the production of antibodies with different isotypes, and the production of memory B Cells (35).

Detailed explanation-3: -This means that before B cells can be induced to make antibody to an infecting pathogen, a CD4 T cell specific for peptides from this pathogen must first be activated to produce the appropriate armed helper T cells. This presumably occurs by interaction with an antigen-presenting dendritic cell (see Section 8-1).

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