BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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B cell
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T cell
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Either A or B
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None of the above
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Detailed explanation-1: -Abstract. Allergic contact dermatitis (ACD) is a T-cell mediated skin inflammation caused by repeated skin exposure to contact allergens. This review summarizes current knowledge on the immunology of ACD. Different phases in ACD are distinguished, i.e. sensitization, elicitation and resolution phases.
Detailed explanation-2: -The most frequent contact allergens are metals, fragrances, and preservatives. ACD clinically manifests as pruritic eczematous lesions, erythema, local papules, and oedema. ACD is a T cell-mediated disease, involving both CD4+ and CD8+ T cells.
Detailed explanation-3: -CD4+ T-cells play a central role in the initiation and maintenance of the allergic airway reaction. By expression of major histocompatibility complex (MHC) class II molecules and allergen-specific T-cell receptors (TCRs) they link innate and adoptive immune responses.