MICROANATOMY

Detailed explanation-1: -Additionally, macrophages release chemokines, leukotrienes, prostaglandins, and complement. All of these molecules, in concert, may induce increased vascular permeability and recruitment of inflammatory cells.

Detailed explanation-2: -The CD4 receptor and MHC class II molecules activate the helper T-cells. The helper T-cells release molecules called cytokines. Cytokines send messages to other immune cells to start an immune response.

Detailed explanation-3: -They attract anti-inflammatory cytokines, which mediate vascular growth and have microcidal properties, to the wound site. Macrophages have very positive effects and maintain tissue homeostasis within humans, however they can also contribute to disease.