BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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B cell
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T cell
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Either A or B
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None of the above
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Detailed explanation-1: -The majority of mature B cells outside of the GALT reside within lymphoid follicles of the spleen and lymph nodes, where they encounter and respond to T cell–dependent foreign antigens bound to follicular dendritic cells (DCs), proliferate, and either differentiate into plasma cells or enter GC reactions.
Detailed explanation-2: -Upon stimulation by a T cell, which usually occurs in germinal centers of secondary lymphoid organs such as the spleen and lymph nodes, the activated B cell begins to differentiate into more specialized cells. Germinal center B cells may differentiate into memory B cells or plasma cells.
Detailed explanation-3: -As they develop, B cells go through 6 stages: They start as common lymphoid progenitor cells, then become early pro-B cells, then late pro-B cells, then large pre-b cells, then small pre-B cells, and finally immature B cells.