MICROANATOMY

Detailed explanation-1: -The first line of defence (or outside defence system) includes physical and chemical barriers that are always ready and prepared to defend the body from infection. These include your skin, tears, mucus, cilia, stomach acid, urine flow, ‘friendly’ bacteria and white blood cells called neutrophils.

Detailed explanation-2: -The innate immune system is the body’s first line of defense against germs entering the body.

Detailed explanation-3: -The innate immune responses are the first line of defense against invading pathogens. They are also required to initiate specific adaptive immune responses. Innate immune responses rely on the body’s ability to recognize conserved features of pathogens that are not present in the uninfected host.

Detailed explanation-4: -“White blood cells are among other places located in the oral mucosa, and they represent the body’s first line of defence against infectious agents. The mucus in the mouth causes the white blood cells to throw out a ‘net’ that traps bacteria”, explains Ole Sørensen from the Division of Infection Medicine.