MICROANATOMY

Detailed explanation-1: -Albumin is synthesized in the liver. The rate of synthesis is constant in normal individuals at 150 to 250 mg/kg/day, resulting in the production of 10 to 18 g of albumin daily in a 70-kg man. The liver produces albumin at less than half of its capacity.

Detailed explanation-2: -Serum albumin accounts for 55% of blood proteins, is a major contributor to maintaining the oncotic pressure of plasma and assists, as a carrier, in the transport of lipids and steroid hormones.

Detailed explanation-3: -Albumin is the most predominant circulating protein in healthy adults (normal physiological concentration is 0.6 Mm). It is synthesized in the liver and it causes 80% of plasma colloid osmotic pressure (COP).