MICROANATOMY

Detailed explanation-1: -Glucagon is a hormone that triggers liver glycogen to convert back into glucose and to enter your bloodstream so that your body can use it for energy.

Detailed explanation-2: -Glucagon’s role in the body is to prevent blood glucose levels dropping too low. To do this, it acts on the liver in several ways: It stimulates the conversion of stored glycogen (stored in the liver) to glucose, which can be released into the bloodstream. This process is called glycogenolysis.

Detailed explanation-3: -Insulin allows the cells in the muscles, fat and liver to absorb glucose that is in the blood. The glucose serves as energy to these cells, or it can be converted into fat when needed. Insulin also affects other metabolic processes, such as the breakdown of fat or protein.

Detailed explanation-4: -Following secretion, glucagon travels to the liver, where it stimulates glycogenolysis. The vast majority of glucose that is released from glycogen comes from glucose-1-phosphate, which is formed when the enzyme glycogen phosphorylase catalyzes the breakdown of the glycogen polymer.

Detailed explanation-5: -Hormonal regulation of glycogen synthesis and breakdown is done by hormones insulin and glucagon. Glycogen synthase stimulates glycogen synthesis. Whenever the blood glucose level rises, the levels of glucose-6-phosphate rises. Glucose-6-phosphate stimulates glycogen synthase and thus glycogen synthesis occurs.